Welcome to PANCREAZE Advantage

A patient support program for qualifying patients and caregivers that offers savings on your prescriptions as well as monthly discounts on a selection of products to support EPI patients.

Benefits include:

Monthly savings on your PANCREAZE prescription
out-of-pocket costs

With the PANCREAZE® Advantage co-pay card, you may pay as little as $0 on your co-pay for your PANCREAZE prescription with a maximum benefit of up to $100 per prescription fill per month.* Your out-of-pocket expense may vary.

Monthly savings on products to support your EPI needs

Patients and caregivers can choose from and save monthly on a selection of products formulated for EPI patients deficient in vitamins A, D, E and K at the VIVUS Amazon storefront.



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*Patient Co-Pay Eligibility, Terms, and Conditions

Eligible patients may pay a minimum of $0 and receive up to $100 off the patient’s co-pay or out-of-pocket expenses for a 30-day supply of PANCREAZE® (pancrelipase) capsules. Patient Instructions: In order to redeem the offer, you must have a valid prescription for PANCREAZE®. This offer may not be redeemed for cash. By using this offer, you are certifying that you meet the eligibility criteria and will comply with the terms and conditions below.

Terms and conditions: Offer is not transferable. Patients are not eligible if they are covered in whole or in part by any state program or federal healthcare program, including, but not limited to, Medicare or Medicaid (including Medicaid managed care), Medigap, VA, DOD,or TRICARE. Only valid in the U.S. and Puerto Rico. Offer void where prohibited by law, taxed, or restricted. Other restrictions may apply. This program is not health insurance. VIVUS, Inc. has the right to rescind, revoke, or amend this program at any time without notice. Your participation in this program confirms that this offer is consistent with your insurance coverage and that you will report the value received if required by your insurance provider. When you use this card, you are certifying that you understand and will comply with the program rules, terms, and conditions.

VIVUS Amazon Store and Product Conditions

VIVUS provides eligible PANCREAZE patients or caregivers of eligible patients under the age of 18, a monthly discount. Eligible patients or caregivers of eligible patients will be issued Amazon single-use claim codes on a monthly basis that can be redeemed and applied to the purchase of products available in the VIVUS Amazon store. VIVUS reserves the right to expire these claim codes at any time, delete or modify the amount of the benefit, and change the products offered in its Amazon store. By registering for the PANCREAZE Advantage program, and by using this site, you are authorizing VIVUS or its designee to contact you by telephone, direct mail or email in order to receive the benefits and verify continued eligibility. VIVUS reserves the right to revoke eligibility and access to these monthly codes based upon proof of prescription and/or PANCREAZE use.


What is the most important information I should know about PANCREAZE®?​

PANCREAZE® may increase your chance of having a serious, rare bowel disorder called fibrosing colonopathy that may require surgery. The risk of having this condition may be reduced by following the dosing instructions that your healthcare provider gave you.

Take PANCREAZE® exactly as prescribed by your doctor. Do not take more or less PANCREAZE® than directed by your doctor.

Call your doctor right away if you have any unusual or severe stomach area (abdominal) pain, bloating, trouble passing stool (having bowel movements), nausea, vomiting, or diarrhea.

What should I tell my doctor before taking PANCREAZE®?

Tell your doctor if you:

  • are allergic to pork (pig) products
  • have a history of blockage of your intestines, or scarring or thickening of your bowel wall (fibrosing colonopathy)
  • have gout, kidney disease, or high blood uric acid (hyperuricemia)
  • have trouble swallowing capsules
  • have any other medical condition
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

PANCREAZE® may cause serious side effects, including:

PANCREAZE® may cause serious side effects, including:

  • A rare bowel disorder called fibrosing colonopathy
  • Irritation of the inside of your mouth. This can happen if PANCREAZE® is not swallowed completely
  • Increase in blood uric acid levels. This may cause worsening of swollen, painful joints (gout) caused by an increase in your blood uric acid levels
  • Allergic reactions including trouble with breathing, skin rashes, or swollen lips

The most common side effects include pain in your stomach (abdominal pain) and gas.

These are not all the side effects of PANCREAZE®. Talk to your doctor about any side effect that bothers you or does not go away. You may report side effects to the FDA at 1-800-FDA-1088 or You may also report side effects to VIVUS, Inc. at 1-888-998-4887.

How do I take PANCREAZE®?

  • Do not crush or chew the PANCREAZE® capsules or their contents, and do not hold the capsule or contents in your mouth. Take PANCREAZE® exactly as your doctor tells you. Read the Medication Guide for directions on how to give PANCREAZE® to adults and children (children older than 12 months).
  • Read the Medication Guide for directions on how to give PANCREAZE® to infants (children up to 12 months).

Please read the PANCREAZE® Medication Guide and PANCREAZE® Product Information and discuss any questions you have with your doctor.